Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
KMT2DENSG00000167548      1                                1                                1                    1                                1          
ARID4AENSG00000032219                                                                                                                                    
NCOA1ENSG00000084676                                                                                                                                    
ZGPATENSG00000197114                                                                                                                                    
PHF20L1ENSG00000129292                                                                                                                                    
LBRENSG00000143815                                                                                                                                    
AIREENSG00000160224                                                                                                                                    
PHF7ENSG00000010318                                                                                                                                    
JADE1ENSG00000077684                                                                                                      1                              
FMR1ENSG00000102081                                                                                                                                    
MLLT10ENSG00000078403          1                                                                                                                          
SMYD4ENSG00000186532                                                                                                                                    
ZMYND11ENSG00000015171                                                                                                                                    
AKAP1ENSG00000121057                                                                  1                                                                  
PCMT1ENSG00000120265                                                                                                                                    
SPIN3ENSG00000204271                                                                                                                                    
TDRKHENSG00000182134                                                                                                                                    
METTL21AENSG00000144401                                                                                                                                    
PRDM11ENSG00000019485                                                                                                                                    
TDRD9ENSG00000156414                                                                                                                                    

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