Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
ARAFENSG00000078061                                                                  1                                                        1          
SUV39H1ENSG00000101945                                                                                                                                    
PHF8ENSG00000172943                                                                                                                                    
MTRNR2L10ENSG00000256045                                                                                                                                    
TAF1ENSG00000147133                                                                  1                                                        1          
KLHL4ENSG00000102271                                                                                                                                    
TEX13AENSG00000268629                                                                                                                                    
MORC4ENSG00000133131                                                                                                                                    
PRPS1ENSG00000147224                                                                                                                                    
ATG4AENSG00000101844                                                                                                                                    
COL4A6ENSG00000197565                                                                                                                                    
KLHL13ENSG00000003096                                                                                                                                    
IKBKGENSG00000269335                                                                                                                                    
AMELYENSG00000099721                                                                                                                                    
PRKYENSG00000099725                                                                                                                                    
INTS12ENSG00000138785                                                                                                                                    
ORC1ENSG00000085840                                                                                                                                    
MPHOSPH8ENSG00000196199                                                                                                                                    
BRPF1ENSG00000156983                                                                                                                                    
CHD9ENSG00000177200                                                                                                                                    

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