Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
NR5A1ENSG00000136931                                                                                                                                    
NR6A1ENSG00000148200                                                                                                                                    
CDK9ENSG00000136807                                                                                                                                    
ENDOGENSG00000167136                                                                                                                                    
LAMC3ENSG00000050555                                                                                                                                    
WDR5ENSG00000196363                                                                                                                                    
RXRAENSG00000186350      1                                                                                                                              
PMPCAENSG00000165688                                                                                                                                    
EGFL7ENSG00000172889                                                                                                                                    
PRPS2ENSG00000101911                                                                                                                                    
TMSB4XENSG00000205542                                                                                                                                    
EGFL6ENSG00000198759                                                                                                                                    
CA5BENSG00000169239                                                                                                                                    
SMSENSG00000102172                                                                      1                                                              
PDK3ENSG00000067992                                                                                                                                    
NR0B1ENSG00000169297                                                                                                                                    
OTCENSG00000036473                                                                                                                                    
DDX3XENSG00000215301              1                                                                                        1                              
DUSP21ENSG00000189037                                                                                                                                    
RBM10ENSG00000182872      1                                                            1                                                                  

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