Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SLC9A3ENSG00000066230                                                                                                                                    
OPN3ENSG00000054277                                                                                                                                    
PLATENSG00000104368                                                                                                                                    
TMEM123ENSG00000152558                                                                                                                                    
CD59ENSG00000085063                                                                                                                                    
PDGFAENSG00000197461                                                                                                                                    
SLC4A11ENSG00000088836                                                                                                                                    
SLC15A1ENSG00000088386                                                                                                                                    
IL1RAPENSG00000196083                                                                                                                                    
ATRNENSG00000088812                                                                                                                                    
DUSP15ENSG00000149599                                                                                                                                    
LIFRENSG00000113594                                                                                                                                    
EPHB3ENSG00000182580                                                                                                                                    
CLCN2ENSG00000114859                                                                                                                                    
IGSF8ENSG00000162729                                                                                                                                    
GPRC5CENSG00000170412                                                                                                                                    
SLCO4A1ENSG00000101187                                                                                                                                    
ADCY8ENSG00000155897                                                                                                                                    
RXFP4ENSG00000173080                                                                                                                                    
FGFR4ENSG00000160867                                                                                                                                    

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