Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PMPCBENSG00000105819                                                                                                                                    
PSMC2ENSG00000161057                                      1                                                                                              
LAMB4ENSG00000091128                                                                                                                                    
LEPENSG00000174697                                                                                                                                    
CEP41ENSG00000106477                                                                                                                                    
AKR1B1ENSG00000085662                                                                                                                                    
AGBL3ENSG00000146856                                                                                                                                    
AKR1D1ENSG00000122787                                                                                                                                    
PARP12ENSG00000059378                                                                                                                                    
CASP2ENSG00000106144                                                                                                                                    
EZH2ENSG00000106462                                                                                                                                    
DEFA1ENSG00000206047                                                                                                                                    
OR7E125PENSG00000177306                                                                                                                                    
TNKSENSG00000173273                                                                                                                                    
OR7E8PENSG00000177400                                                                                                                                    
FGF20ENSG00000078579                                                                                                                                    
MTMR7ENSG00000003987                                                                                                                                    
ATP6V1B2ENSG00000147416                                                                                                                                    
PBKENSG00000168078                                                                                                                                    
PNOCENSG00000168081                                                                                                                                    

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