Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PDE7BENSG00000171408                                                                                                                                    
PPIL4ENSG00000131013                                                                                                                          1          
PSMB1ENSG00000008018                                                                                                                                    
PSMG3ENSG00000157778                                                                                                                                    
PMS2ENSG00000122512                                                                                                                                    
EIF2AK1ENSG00000086232                                                                                                                                    
COL28A1ENSG00000215018                                                                                                                                    
PRPS1L1ENSG00000229937                                                                                                                                    
PDE1CENSG00000154678                                                                                                                                    
NME8ENSG00000086288                                                                                                                                    
PSMA2ENSG00000106588                                                                                                                                    
PPIAENSG00000196262                                                                                                                                    
FKBP6ENSG00000077800                                                                                                                                    
LIMK1ENSG00000106683                                                                                                                                    
EIF4HENSG00000106682                                                                                                                                    
STYXL1ENSG00000127952                                                                                                                                    
YWHAGENSG00000170027                                                                                                                                    
DBF4ENSG00000006634                                                                                                                                    
PDK4ENSG00000004799                                                                                                                                    
VGFENSG00000128564                                                                                                                                    

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