Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
HMGB2ENSG00000164104                                                                                                                                    
NEIL3ENSG00000109674                                                                                                                                    
AGAENSG00000038002                                                                                                                                    
PRIMPOLENSG00000164306                                                                                                                                    
BRD9ENSG00000028310                                                                                                                                    
ADAMTS16ENSG00000145536                                                                                                                                    
ADAMTS12ENSG00000151388                                                                                                                                    
PELOENSG00000152684                                                                                                                                    
ESM1ENSG00000164283                                                                                                                                    
PPWD1ENSG00000113593                                                                                                                                    
SMN1ENSG00000172062                                                                                                                                    
MCCC2ENSG00000131844      1                                                                                                                              
PDE8BENSG00000113231                                                                                                                                    
BHMT2ENSG00000132840                                                                                                                                    
BHMTENSG00000145692                                                                                                                                    
DHFRENSG00000228716                                                                                                                                    
HAPLN1ENSG00000145681                                                                                                                                    
EDIL3ENSG00000164176                                                                  1                                                                  
NR2F1ENSG00000175745                                                                                                                                    
LECT2ENSG00000145826                                                                                                                                    

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