Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TAB1ENSG00000100324                                                                                                                                    
XPNPEP3ENSG00000196236                                                                                                                                    
EP300ENSG00000100393      1    1    1                1        1                                1                                                    1          
PPARAENSG00000186951                                                                                                                                    
BRD1ENSG00000100425                                                                                                                          1          
PPARGENSG00000132170                                                                                                                                    
OXNAD1ENSG00000154814                                                                                                                                    
PLCL2ENSG00000154822                                                                                                                                    
KAT2BENSG00000114166                                                                                                                                    
NR1D2ENSG00000174738      1                                                                                                                              
THRBENSG00000151090                                                                                                                                    
RARBENSG00000077092          1                                                                                                                          
TOP2BENSG00000077097                                                                                                      1    1                          
MLH1ENSG00000076242                                                                                                                                    
PLCD1ENSG00000187091                                                                                                                                    
CCKENSG00000187094                                                                                                                                    
SETD2ENSG00000181555                                              1    1        1        1    1    1                1            1                              
KLHL18ENSG00000114648                                                                                                                                    
PTPN23ENSG00000076201                                                                                                                                    
CDC25AENSG00000164045                                                                                                                                    

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