Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
HDAC4ENSG00000068024                                                                                                                                    
OTOSENSG00000178602                                                                                                                                    
RNPEPL1ENSG00000142327                                                                                                                                    
ATG4BENSG00000168397                                                                                                                                    
RSPO4ENSG00000101282                                                                                                                                    
GNRH2ENSG00000125787                                                                                                                                    
CDC25BENSG00000101224                                                                                                                                    
RBBP9ENSG00000089050                                                                                                                                    
DNMT3BENSG00000088305                                                                                                                                    
GSSENSG00000100983                                                                                                                                    
SOGA1ENSG00000149639                                                                                                                                    
TOP1ENSG00000198900                                                                                                          1                          
EMILIN3ENSG00000183798                                                                                                                                    
L3MBTL1ENSG00000185513                                                                                                                                    
HNF4AENSG00000101076                                                                                                                                    
WISP2ENSG00000064205                                                                                                                                    
SEMG2ENSG00000124157                                                                                                                                    
SPINT3ENSG00000101446                                                                                                                                    
TP53RKENSG00000172315                                                                                                                                    
NCOA3ENSG00000124151                                                                                                                                    

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