Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
IL1BENSG00000125538                                                                                                                                    
IL37ENSG00000125571                                                                                                                                    
IL36GENSG00000136688                                                                                                                                    
IL36BENSG00000136696                                                                                                                                    
IL36RNENSG00000136695                                                                                                                                    
IL1F10ENSG00000136697                                                                                                                                    
C1QL2ENSG00000144119                                                                                                                                    
PTPN18ENSG00000072135                                                                                                                                    
TNFAIP6ENSG00000123610                                                                                                                                    
NR4A2ENSG00000153234                                                                                                                                    
PSMD14ENSG00000115233                                                                                                                                    
PPIGENSG00000138398                                                                                                                                    
KLHL23ENSG00000213160                                                                                                                                    
METAP1DENSG00000172878                                                                                                                                    
pkENSG00000091436                                                                                                                                    
STAT1ENSG00000115415      1                                                                                                                              
PLCL1ENSG00000115896                                                                                                                                    
CTDSP1ENSG00000144579                                                              1                                                                      
PDE6DENSG00000156973                                                                                                                                    
KLHL30ENSG00000168427                                                                                                                                    

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