Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
ADAMTS10ENSG00000142303                                                                                                                                    
ANGPTL6ENSG00000130812                                                                                                                                    
KEAP1ENSG00000079999                                      1                        1    1    1                                                              
PODNL1ENSG00000132000                                                                                                                                    
SAMD1ENSG00000141858                                                                                                                                    
CASP14ENSG00000105141                                                                                                                                    
NR2F6ENSG00000160113                                                                                                                                    
JAK3ENSG00000105639                                                                                                                                    
PIK3R2ENSG00000105647                                                                                                                          1          
CILP2ENSG00000160161                                                                                                                                    
SBSNENSG00000189001                                                                                                                                    
LGALS7BENSG00000178934                                                                                                                                    
SYCNENSG00000179751                                                                                                                                    
ITPKCENSG00000086544                                                                                                                                    
EGLN2ENSG00000269858                                                                                                                                    
RELBENSG00000104856                                                                                                                                    
SULT2A1ENSG00000105398                                                                                                                                    
LIG1ENSG00000105486                                                                                                                                    
CARD8ENSG00000105483                                                                                                                                    
SULT2B1ENSG00000088002                                                                                                                                    

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