Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
EIF4A1ENSG00000161960                                                                                                                                    
TP53ENSG00000141510  1    1    1    1        1        1    1    1    1            1    1    1    1    1    1    1    1        1    1    1    1    1                1    1      
MAPK7ENSG00000166484                                                                                                                                    
MTRNR2L1ENSG00000256618                                                                                                                                    
LGALS9ENSG00000168961                                                                                                                                    
NOS2ENSG00000007171                                                                                                                                    
SDF2ENSG00000132581                                                                                                                                    
SSH2ENSG00000141298                                                                                                                                    
BLMHENSG00000108578                                                                                                                                    
CCL8ENSG00000108700                                                                                                                                    
CCL13ENSG00000181374                                                                                                                                    
CCL18ENSG00000275385                                                                                                                                    
CCL3L3ENSG00000276085                                                                                                                                    
PSMB3ENSG00000277791                                                                                                                                    
CDK12ENSG00000167258                                                                  1            1                                            1          
PNMTENSG00000141744                                                                                                                                    
CSF3ENSG00000108342                                                                                                                                    
THRAENSG00000126351                                                                                                                                    
NR1D1ENSG00000126368                                                                                                                                    
TOP2AENSG00000131747                                                                              1                            1                1          

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