Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TPH2ENSG00000139287                                                                                                                                    
NTSENSG00000133636                                                                                                                                    
LTA4HENSG00000111144                                                                                                                                    
NR1H4ENSG00000012504                                                                                                                                    
PAHENSG00000171759                                                                                                                                    
PTPN11ENSG00000179295                      1            1                    1    1                                                                          
KSR2ENSG00000171435                                                                                                                                    
PRKAB1ENSG00000111725                                                                                                                                    
HPDENSG00000158104                                                                                                                                    
NCOR2ENSG00000196498                                                                                                                          1          
CDK8ENSG00000132964                                                                      1                                                              
HSPH1ENSG00000120694                                                                                                                                    
KBTBD6ENSG00000165572                                                                                                                                    
KBTBD7ENSG00000120696                                                                                                                                    
SETDB2ENSG00000136169                                                                                                                                    
GUCY1B2ENSG00000123201                                                                                                                                    
KLHL1ENSG00000150361                                                                                                                                    
KLF5ENSG00000102554      1        1                                                                                                                      
UCHL3ENSG00000118939                                                                                                                                    
STK24ENSG00000102572                                                                                                                                    

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