Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SUV39H2ENSG00000152455                                                                                                                                    
PRTFDC1ENSG00000099256                                                                                                                                    
MTRNR2L7ENSG00000256892                                                                                                                                    
MTRNR2L5ENSG00000249860                                                                                                                                    
SIRT1ENSG00000096717                                                                                                                                    
SPOCK2ENSG00000107742                                                                                                                                    
PLA2G12BENSG00000138308                                                                                                                                    
ADKENSG00000156110                                                                                                                                    
PPIFENSG00000108179                                                                                                                                    
MAT1AENSG00000151224                                                                                                                                    
RNLSENSG00000184719                                                                                                                                    
LIPJENSG00000204022                                                                                                                                    
IFIT1ENSG00000185745                                                                                                                                    
TNKS2ENSG00000107854                                                                                                                                    
FGFBP3ENSG00000174721                                                                                                                                    
KIF11ENSG00000138160                                                                                                                                    
SFRP5ENSG00000120057                                                                                                                                    
CPN1ENSG00000120054                                                                                                                                    
MGEA5ENSG00000198408                                                                                                                                    
NFKB2ENSG00000077150          1                                                                                                                          

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