Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
MDM4ENSG00000198625                                                                                                                                    
IL10ENSG00000136634                                                                                                                                    
SMYD2ENSG00000143499                                                                                                                                    
BPNT1ENSG00000162813                                                                                                                                    
TAF1AENSG00000143498                                                                                                                                    
CAPN8ENSG00000203697                                                                                                                                    
LEFTY1ENSG00000243709                                                                                                                                    
LEFTY2ENSG00000143768                                                                                                                                    
H3F3AENSG00000163041              1                                                                                                                      
PARP1ENSG00000143799          1                                                                                                                          
ITPKBENSG00000143772                                                                                                                                    
CAPN9ENSG00000135773                                                                                                                                    
EGLN1ENSG00000135766                                                                                                                                    
MTRENSG00000116984                                                                  1                                                                  
PITRM1ENSG00000107959                                                                                                                                    
AKR1C2ENSG00000151632                                                                                                                                    
AKR1C1ENSG00000187134                                                                                                                                    
AKR1C3ENSG00000196139                                                                                                                                    
AKR1C8PENSG00000264006                                                                                                                                    
AKR1C4ENSG00000198610                                                                                                                                    

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