Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
RSPO1ENSG00000169218                                                                                                                                    
PPIEENSG00000084072                                                                                                                                    
BMP8BENSG00000116985                                                                                                                                    
EDN2ENSG00000127129                                                                                                                                    
PPIHENSG00000171960                                                                                                                                    
KDM4AENSG00000066135                                                                  1                                                                  
TESK2ENSG00000070759                                                                                                                                    
PIK3R3ENSG00000117461                                                                                                                                    
AGBL4ENSG00000186094                                                                                                                                    
GPX7ENSG00000116157                                                                                                                                    
CPT2ENSG00000157184                                                                                                                                    
JUNENSG00000177606                                                                                                                                    
USP1ENSG00000162607                                                                                                                                    
ATG4CENSG00000125703                                                                                                                                    
JAK1ENSG00000162434                                                                                                                          1          
ZRANB2ENSG00000132485                                                                                                                                    
TNNI3KENSG00000116783                                                                                                                                    
AMY2BENSG00000240038                                                                                                                                    
AMY2AENSG00000243480                                                                                                                                    
AMY1AENSG00000237763                                                                                                                                    

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