Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
KLHL21ENSG00000162413                                                                                                                                    
MTORENSG00000198793                                                                                                                                    
CASP9ENSG00000132906                                                                                                                                    
MFAP2ENSG00000117122                                                                                                                                    
PADI1ENSG00000142623                                                                                                                                    
PADI3ENSG00000142619                                                                                                                                    
AKR7LENSG00000211454                                                                                                                                    
AKR7A3ENSG00000162482                                                                                                                                    
AKR7A2ENSG00000053371                                                                                                                                    
CDAENSG00000158825                                                                                                                                    
C1QCENSG00000159189                                                                                                                                    
SFNENSG00000175793                                                                                                                                    
NR0B2ENSG00000131910                                                                                                                                    
MATN1ENSG00000162510                                                                                                                                    
TINAGL1ENSG00000142910                                                                                                                                    
KHDRBS1ENSG00000121774                                                                                                                                    
HDAC1ENSG00000116478                                                                                                                                    
YARSENSG00000134684                                                                                                                                    
AK2ENSG00000004455                                                                                                                                    
PSMB2ENSG00000126067                                                                                                                                    

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