Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
LARSENSG00000133706                                                                  1                                                                  
SPINK1ENSG00000164266                                                                                                                                    
SCGB3A2ENSG00000164265                                                                                                                                    
SPINK5ENSG00000133710                                                                                                                                    
SPINK7ENSG00000145879                                                                                                                                    
RARSENSG00000113643                                                                                                                                    
DUSP1ENSG00000120129                                                                                                                                    
SCGB3A1ENSG00000161055                                                                                                                                    
NQO2ENSG00000124588                                                                                                                                    
PRPF4BENSG00000112739                                                                  1                                                                  
MAKENSG00000111837                                                                                                                                    
GMPRENSG00000137198                                                                                                                                    
KDM1BENSG00000165097      1                                                                                                                              
GPX5ENSG00000224586                                                                                                                                    
C6orf15ENSG00000204542                                                                                                                                    
BRD2ENSG00000204256                                                                                                                                    
PPARDENSG00000112033                                                                                                                                    
FKBP5ENSG00000096060                                                                                                                                    
CLPSENSG00000137392                                                                                                                                    
MAPK13ENSG00000156711                                                                                                                                    

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