Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SFRP2ENSG00000145423                                                                                                                                    
GUCY1B3ENSG00000061918                                                                                                                                    
CTSOENSG00000256043                                                                                                                                    
FSTL5ENSG00000168843                                                                                                                                    
CBR4ENSG00000145439                                                                                                                                    
HPGDENSG00000164120                                                                                                                                    
MTRRENSG00000124275                                                                                                                                    
TARSENSG00000113407                                                                                          1                                          
AGXT2ENSG00000113492                                                                                                                                    
EGFLAMENSG00000164318                                                                                                                                    
ADAMTS6ENSG00000049192                                                                                                                                    
NLNENSG00000123213                                                                                                                                    
CCNB1ENSG00000134057                                                                                                                                    
SMN2ENSG00000205571                                                                                                                                    
CARTPTENSG00000164326                                                                                                                                    
AGGF1ENSG00000164252                                                                                                                                    
CCNHENSG00000134480                                                                                                                                    
CDKL3ENSG00000006837                                                                                                                                    
HDAC3ENSG00000171720                                                                                                                                    
NR3C1ENSG00000113580      1                                                                                                                              

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