Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
NEK4ENSG00000114904                                                                                                                                    
ITIH3ENSG00000162267                                                                                                                                    
TKTENSG00000163931                                                                                                                                    
RETNLBENSG00000163515                                                                                                                                    
PARP9ENSG00000138496                                                                                                                                    
UMPSENSG00000114491                                                                                                                                    
TRHENSG00000170893                                                                                                                                    
PIK3CBENSG00000051382                                                                                                                                    
RBP2ENSG00000114113                                                                                                                                    
RBP1ENSG00000114115                                                                                                                                    
CPB1ENSG00000153002                                                                                                                                    
CPA3ENSG00000163751                                                                                                                                    
VN2R1PENSG00000174930                                                                                                                                    
LXNENSG00000079257                                                                                                                                    
PIK3CAENSG00000121879      1    1    1        1        1    1    1                    1        1    1                        1            1                1    1      
SPON2ENSG00000159674                                                                                                                                    
RGS12ENSG00000159788                                                                                                                                    
HTRA3ENSG00000170801                                                                                                                                    
LAP3ENSG00000002549                                                                                                                                    
STATHENSG00000126549                                                                                                                                    

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