Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
MAP3K10ENSG00000130758                                                                                                                                    
SPHK2ENSG00000063176                                                                                                                                    
HRCENSG00000130528                                                                                                                                    
PRMT1ENSG00000126457                                                                                                                                    
POLD1ENSG00000062822                                                                                                                                    
KLK1ENSG00000167748                                                                                                                                    
LAIR2ENSG00000167618                                                                                                                                    
GALPENSG00000197487                                                                                                                                    
MATN3ENSG00000132031                                                                                                                                    
FKBP1BENSG00000119782                                                                                                                                    
TP53I3ENSG00000115129                                                                                                                                    
RBKSENSG00000171174                                                                                                                                    
CAPN14ENSG00000214711                                                                                                                                    
XDHENSG00000158125                                                                                                                                    
VITENSG00000205221                                                                                                                                    
EIF2AK2ENSG00000055332                                                                                                                                    
CDKL4ENSG00000205111                                                                                                                                    
MAP4K3ENSG00000011566                                                                                                                                    
PKDCCENSG00000162878                                                                                                                                    
REG3GENSG00000143954                                                                                                                                    

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