Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SERPINB10ENSG00000242550                                                                                                                                    
CNDP1ENSG00000150656                                                                                                                                    
ZADH2ENSG00000180011                                                                                                                                    
DOT1LENSG00000104885                                                                                                                                    
DPP9ENSG00000142002                                                                                                                                    
LONP1ENSG00000196365                                                                                                                                    
NRTNENSG00000171119                                                                                                                                    
CLPPENSG00000125656                                                                                                                                    
RETNENSG00000104918                                                                                                                                    
PIN1ENSG00000127445                                                                                                                                    
DNMT1ENSG00000130816                                                                                                      1                              
ACP5ENSG00000102575                                                                                                                                    
RLN3ENSG00000171136                                                                                                                                    
BRD4ENSG00000141867                                                                                                                                    
PDE4CENSG00000105650                                                                                                                                    
CCNE1ENSG00000105173                                                                                                                                    
PEPDENSG00000124299                                                                                                                                    
KRTDAPENSG00000188508                                                                                                                                    
DMKNENSG00000161249                                                                                                                                    
DYRK1BENSG00000105204                                                                                                                                    

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