Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
NEK3ENSG00000136098                                                                                                                                    
TPP2ENSG00000134900                                                                                                      1                              
COL4A1ENSG00000187498                                                                                                                                    
GAS6ENSG00000183087                                                                                                                                    
PNPENSG00000198805                                                                                                                                    
SUPT16HENSG00000092201                      1                                                                                                              
PSMB5ENSG00000100804                                                                                                                                    
BCL2L2-PABPN1ENSG00000258643                                                                                                                                    
DHRS4ENSG00000157326                                                                                                                                    
RNF31ENSG00000092098                                                                                                                                    
RABGGTAENSG00000100949                                                                                                                                    
PSMA6ENSG00000100902      1                                                                                                                              
STYXENSG00000198252                                                                                                                                    
FNTBENSG00000257365                                                                                                                                    
ESRRBENSG00000119715                                                                                                                                    
PLCB2ENSG00000137841                                                                                                                                    
CAPN3ENSG00000092529                                                                                                                                    
TGM7ENSG00000159495                                                                                                                                    
HDCENSG00000140287                                                                                                                                    
MAPK6ENSG00000069956                                                                                                                                    

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