Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PATE4ENSG00000237353                                                                                                                                    
FKBP4ENSG00000004478                                                                                                                                    
CCND2ENSG00000118971                                                                                                                                    
DYRK4ENSG00000010219                                                                                                                                    
ACRBPENSG00000111644                                                                                                                                    
PTPN6ENSG00000111679                                                                  1                                                                  
RBP5ENSG00000139194                                                                                                                                    
DUSP16ENSG00000111266                                                                                                                                    
PIK3C2GENSG00000139144                                                                                                                                    
LDHBENSG00000111716                                                                                                                                    
PTHLHENSG00000087494                                                                                                                                    
YARS2ENSG00000139131                                                                                                                                    
YAF2ENSG00000015153                                                                                                                                    
TUBA1BENSG00000123416                                                                                                                                    
TUBA1AENSG00000167552                                                                                                                                    
NR4A1ENSG00000123358                                                                                                                                    
KRT8ENSG00000170421                                                                                                                                    
CSADENSG00000139631                                                                                                                                    
RARGENSG00000172819                                                                                                                                    
PDE1BENSG00000123360                                                                                                                                    

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