Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TXNDC5ENSG00000239264                                                                                                                                    
EDN1ENSG00000078401                                                                                                                                    
COL11A2ENSG00000204248                                                                                                                                    
MAPK14ENSG00000112062                                                                                                                                    
PGCENSG00000096088                                                                                                                                    
CCND3ENSG00000112576                                                                                                                                    
TTBK1ENSG00000146216                                                                                                                                    
IMPG1ENSG00000112706                                                                                                                                    
TTKENSG00000112742                                                                  1                                                        1          
RTN4IP1ENSG00000130347                                                                                                                                    
TUBE1ENSG00000074935                                                                                                                                    
ALDH8A1ENSG00000118514                                                                                                                                    
MAP3K5ENSG00000197442                                                                                                      1                              
MAP3K4ENSG00000085511          1                                                                                                                          
UPP1ENSG00000183696                                                                                                                                    
CCL26ENSG00000006606                                                                                                                                    
TAC1ENSG00000006128                                                                                                                                    
SRPK2ENSG00000135250                                                                                                                                    
IMPDH1ENSG00000106348                                                                                                                                    
PTNENSG00000105894                                                                                                                                    

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