Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
ADORA2BENSG00000170425                                                                                                                                    
ADRA1BENSG00000170214                                                                                                                                    
CHRNEENSG00000108556                                                                                                                                    
LOXENSG00000113083                                                                                                                                    
ERMP1ENSG00000099219                                                                                                                                    
PRSS35ENSG00000146250                                                                                                                                    
GABRB3ENSG00000166206                                                                                                                                    
SLC18A1ENSG00000036565                                                                                                                                    
MCAMENSG00000076706                                                                                                                                    
MFI2ENSG00000163975                                                                                                                                    
MSR1ENSG00000038945                                                                                                                                    
SLC39A8ENSG00000138821                                                                                                                                    
TGFB3ENSG00000119699                                                                                                                                    
NRXN3ENSG00000021645                                                                                                                                    
TNFRSF9ENSG00000049249                                                                                                                                    
ADRA1AENSG00000120907                                                                                                                                    
VCAM1ENSG00000162692                                                                                                                                    
TNFRSF4ENSG00000186827                                                                                                                                    
TNFRSF8ENSG00000120949                                                                                                                                    
SLC7A5ENSG00000103257                                                                                                                                    

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