Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
ACRENSG00000100312                                                                                                                                    
TIMP4ENSG00000157150                                                                                                                                    
NR2C2ENSG00000177463                                                                                                                                    
LYZL4ENSG00000157093                                                                                                                                    
IMPDH2ENSG00000178035                                                                                                                                    
APEHENSG00000164062                                                                                                                                    
SEMA3FENSG00000001617                                                                                                                                    
ITIH1ENSG00000055957                                                                                                                                    
DNASE1L3ENSG00000163687                                                                                                                                    
PARP15ENSG00000173200                                                                                                                                    
ALDH1L1ENSG00000144908                                                                                                                                    
PIK3R4ENSG00000196455                                                                                                                                    
NEK11ENSG00000114670                                                                                                                                    
PCCBENSG00000114054                                                                                                                                    
GRK7ENSG00000114124                                                                                                                                    
OTOL1ENSG00000182447                                                                                                                                    
OSTNENSG00000188729                                                                                                                                    
PDE6BENSG00000133256                                                                                                                                    
STK32BENSG00000152953                                                                                                                                    
FDCSPENSG00000181617                                                                                                                                    

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