Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PTGR2ENSG00000140043                                                                                                                                    
COQ6ENSG00000119723                                                                                                                                    
RPS6KL1ENSG00000198208                                                                                                                                    
VASH1ENSG00000071246                                                                                                                                    
SERPINA12ENSG00000165953                                                                                                                                    
EIF2AK4ENSG00000128829                                                                                                                                    
PLA2G4BENSG00000243708                                                                                                                                    
TTBK2ENSG00000128881                                                                                                                                    
TGM5ENSG00000104055                                                                                                                                    
SORDENSG00000140263                                                                                                                                    
SMAD3ENSG00000166949                      1                                                                                                    1          
CLK3ENSG00000179335                                                                                                                                    
ULK3ENSG00000140474                                                                                                                                    
BCL2A1ENSG00000140379                                                                                                                                    
RLBP1ENSG00000140522                                                                                                                                    
C1QTNF8ENSG00000184471                                                                                                                                    
NPWENSG00000183971                                                                                                                                    
DNASE1L2ENSG00000167968                                                                                                                                    
PRSS33ENSG00000103355                                                                                                                                    
PLK1ENSG00000166851                                                                                                                                    

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