Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
LRRK2ENSG00000188906                                                                                                                                    
SENP1ENSG00000079387                                                                                                                                    
CCNT1ENSG00000129315                                                                                                                                    
DCDENSG00000161634                                                                                                                                    
TAC3ENSG00000166863                                                                                                                                    
WIF1ENSG00000156076                                                                                                                                    
LYZENSG00000090382                                                                                                                                    
UBE2NENSG00000177889                                                                                                                                    
SCYL2ENSG00000136021                                                                                                                                    
PMCHENSG00000183395                                                                                                                                    
ALDH1L2ENSG00000136010                                                                                                                                    
ALDH2ENSG00000111275                                                                                                                                    
ULK1ENSG00000177169                                                                  1    1                                                              
C1QTNF9BENSG00000205863                                                                                                                                    
DHRS12ENSG00000102796                                                                                                                                    
DHRS2ENSG00000100867                                                                                                                                    
COCHENSG00000100473                                                                                                                                    
KLHL28ENSG00000179454                                                                                                                                    
CDKL1ENSG00000100490                                                                                                                                    
MAP3K9ENSG00000006432                                                                                                                                    

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