Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CDC7ENSG00000097046                                                                                                                          1          
HAO2ENSG00000116882                                                                                                                                    
PGLYRP3ENSG00000159527                                                                                                                                    
CLK2ENSG00000176444                                                                                                                                    
CRPENSG00000132693                                                                                                                                    
PPOXENSG00000143224                                                                                                                                    
XCL2ENSG00000143185                                                                                                                                    
XCL1ENSG00000143184                                                                                                                                    
ABL2ENSG00000143322                                                                                                                                    
CTSEENSG00000196188                                                                                                                                    
NEK2ENSG00000117650                                                                                                                                    
IARS2ENSG00000067704                                                                  1                                    1                              
CDC42BPAENSG00000143776          1                                                                                                                          
CDK1ENSG00000170312                                                                                                                                    
SRGNENSG00000122862                                                                                                                                    
HKDC1ENSG00000156510                                                                                                                                    
SFTPDENSG00000133661                                                                                                                                    
CHUKENSG00000213341                                                                                                                                    
PNLIPENSG00000175535                                                                                                                                    
NPSENSG00000214285                                                                                                                                    

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