Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CRISP2ENSG00000124490                                                                                                                                    
DEFB114ENSG00000177684                                                                                                                                    
HDAC2ENSG00000196591                                                                                                                                    
LATS1ENSG00000131023                                                                      1                                                              
RPS6KA2ENSG00000071242                                                                                                                                    
IGFBP1ENSG00000146678                                                                                                                                    
DEFB103AENSG00000176797                                                                                                                                    
LOXL2ENSG00000134013                                                                                                                                    
SLC25A37ENSG00000147454                                                                                                                                    
POLBENSG00000070501                                                                                                                                    
PRKDCENSG00000253729                                                                                                                                    
PDE7AENSG00000205268                                                                                                                                    
ATP6V1C1ENSG00000155097                                                                                                                                    
COLEC10ENSG00000184374                                                                                                                                    
CYP11B2ENSG00000179142                                                                                                                                    
IFNB1ENSG00000171855                                                                                                                                    
ALDH1A1ENSG00000165092                                                                                                      1                              
IARSENSG00000196305                                                                                                                          1          
COL27A1ENSG00000196739                                                                                                                                    
TOR2AENSG00000160404                                                                                                                                    

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