Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
BMP2KENSG00000138756                                                                  1                                                                  
MAPK10ENSG00000109339                                                                                                                                    
HSD17B11ENSG00000198189                                                                                                                                    
ADH5ENSG00000197894                                                                                                                                    
DCLK2ENSG00000170390                                                                                                                                    
KLHL2ENSG00000109466                                                                                                                                    
PRKAA1ENSG00000132356                                                                                                                                    
MAST4ENSG00000069020                                                              1        1                                                              
PCSK1ENSG00000175426                                                                                                                                    
HSD17B4ENSG00000133835                                                                                                                                    
CSNK1G3ENSG00000151292                                                                                                                                    
ALDH7A1ENSG00000164904                                                                                                      1                              
CXCL14ENSG00000145824                                                                                                                                    
SPINK6ENSG00000178172                                                                                                                                    
GRK6ENSG00000198055                                                                                                                                    
MAPK9ENSG00000050748                                                                                                                                    
SERPINB6ENSG00000124570                                                                                                                                    
ALDH5A1ENSG00000112294                                                                                                                                    
MLNENSG00000096395                                                                                                                                    
SLC25A27ENSG00000153291                                                                                                                                    

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