Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
GHRLENSG00000157017                                                                                                                                    
TGM4ENSG00000163810                                                                                                                                    
LARS2ENSG00000011376                                                                                                                                    
PRSS50ENSG00000206549                                                                                                                                    
PRSS45ENSG00000188086                                                                                                                                    
UCN2ENSG00000145040                                                                                                                                    
BAP1ENSG00000163930                                              1    1            1    1        1                                                        1  
FAM19A1ENSG00000183662                                                                                                                                    
PROK2ENSG00000163421                                                                                                                                    
PDIA5ENSG00000065485                                                                                                                                    
TXNRD3ENSG00000197763                                                                                                                                    
AADACL2ENSG00000197953                                                                                                                                    
UTS2BENSG00000188958                                                                                                                                    
BDH1ENSG00000161267                                                                                                                                    
GRK4ENSG00000125388                                                                                                                                    
NMUENSG00000109255                                                                                                                                    
UBA6ENSG00000033178                                                                                                                                    
PF4ENSG00000163737                                                                                                                                    
PPBPENSG00000163736                                                                                                                                    
CXCL11ENSG00000169248                                                                                                                                    

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