Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SLC25A12ENSG00000115840                                                                                                                                    
FRZBENSG00000162998                                                                                                                                    
IGFBP2ENSG00000115457                                                                                                                                    
SPEGENSG00000072195                                                                                                                                    
COL4A3ENSG00000169031                                                                                                                                    
SPP2ENSG00000072080                                                                                                                                    
STK35ENSG00000125834                                                                                                                                    
SMOXENSG00000088826                                                                                                                                    
PAK7ENSG00000101349                                                                                                                                    
PCSK2ENSG00000125851                                                                                                                                    
CST11ENSG00000125831                                                                                                                                    
MYLK2ENSG00000101306                                                                                                                                    
SGK2ENSG00000101049                                                                                                                                    
STK4ENSG00000101109                                                                                                                                    
MOCS3ENSG00000124217                                                                                                                                    
SYNJ1ENSG00000159082                                                                                                                                    
TFF3ENSG00000160180                                                                                                                                    
CSNK1EENSG00000213923                                                                                                      1                              
CHADLENSG00000100399                                                                                                                                    
PIM3ENSG00000198355                                                                                                                                    

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