Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SLC25A21ENSG00000183032                                                                                                                                    
CDKN3ENSG00000100526                                                                                                                                    
RDH12ENSG00000139988                                                                                                                                    
ADCK1ENSG00000063761                                                                                                                                    
RPS6KA5ENSG00000100784                                                                                                                                    
SLC25A29ENSG00000197119                                                                                                                                    
MOKENSG00000080823                                                                                                                                    
BUB1BENSG00000156970                                                                                                                                    
PLA2G4DENSG00000159337                                                                                                                                    
GANCENSG00000214013                                                                                                                                    
ALDH1A2ENSG00000128918                                                                                                                                    
LACTBENSG00000103642                                                                                                                                    
DPP8ENSG00000074603                                                                      1                                                              
CYP11A1ENSG00000140459                                                                                                                                    
ALDH1A3ENSG00000184254          1                                                                                                                          
C16orf89ENSG00000153446                                                                                                                                    
ABATENSG00000183044                                                                                                                                    
IL27ENSG00000197272                                                                                                                                    
CES3ENSG00000172828                                                                                                                                    
CLEC3AENSG00000166509                                                                                                                                    

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