Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CHIAENSG00000134216                                                                                                                                    
ITLN2ENSG00000158764                                                                                                                                    
UHMK1ENSG00000152332                                                                                                                                    
PLA2G4AENSG00000116711                                                                  1                                                                  
CHIT1ENSG00000133063                                                                                                                                    
ADCK3ENSG00000163050                                                                                                                                    
NID1ENSG00000116962                                                                                                                                    
ACTN2ENSG00000077522                                                                      1                                                              
NLRP3ENSG00000162711                                                                                                                                    
MAP3K8ENSG00000107968                                                                                                                                    
ALOX5ENSG00000012779                                                                                                                                    
MSMBENSG00000263639                                                                                                                                    
MAPK8ENSG00000107643                                                                                                                                    
TYSND1ENSG00000156521                                                                                                                                    
PNLIPRP1ENSG00000187021                                                                                                                                    
STK33ENSG00000130413                                                                                                                                    
RPS6KA4ENSG00000162302                                                                                                                                    
CDC42BPGENSG00000171219                                                                                                                                    
FGF19ENSG00000162344                                                                                                                                    
PGRENSG00000082175                                                                                                                                    

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