Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TRRAPENSG00000196367      1                        1                                                                                                      
HIPK2ENSG00000064393                                                                                                                                    
DEFB103BENSG00000177243                                                                                                                                    
NAT2ENSG00000156006                                                                                                                                    
HTRA4ENSG00000169495                                                                                                                                    
PSKH2ENSG00000147613                                                                                                                                    
CYP11B1ENSG00000160882                                                                                                                                    
MSMPENSG00000215183                                                                                                                                    
DHRSXENSG00000169084                                                                                                                                    
PIM2ENSG00000102096                                                                                                                                    
PAK3ENSG00000077264                                                                                                                                    
ALDH4A1ENSG00000159423                                                                                                                                    
PLA2G2DENSG00000117215                                                                                                                                    
PLA2G2CENSG00000187980                                                                                                                                    
RPS6KA1ENSG00000117676                                                                                                                                    
TSSK3ENSG00000162526                                                                                                                                    
COL9A2ENSG00000049089                                                                                                                                    
TXNDC12ENSG00000117862                                                                                                                                    
SLC25A24ENSG00000085491                                                                                                                                    
CHI3L2ENSG00000064886                                                                                                                                    

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