Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
MKNK1ENSG00000079277                                                                                                                                    
PRKAA2ENSG00000162409                                                                                                                                    
FAM19A3ENSG00000184599                                                                                                                                    
FDPSENSG00000160752                                                                                                                                    
NUAK2ENSG00000163545                                      1                                                                                              
IKBKEENSG00000263528                                                                                                                                    
MAPKAPK2ENSG00000162889                                                                                                                                    
WNT9AENSG00000143816                                                                                                                                    
CAMK1DENSG00000183049                                                                                                                                    
CYP2C18ENSG00000108242                                                                                                                                    
CYP2C19ENSG00000165841                                                                                                                          1          
CYP2C9ENSG00000138109                                                                                                                                    
CRTAC1ENSG00000095713                                                                                                                                    
SLC25A28ENSG00000155287                                                                                                                                    
CYP17A1ENSG00000148795                                                                                                                                    
PAOXENSG00000148832                                                                                                                                    
LDHAENSG00000134333                                                                                                                                    
HIPK3ENSG00000110422                                                                                                                                    
GANABENSG00000089597                                                                                                          1                          
MMP20ENSG00000137674                                                                                                                                    

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