Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SLC25A34ENSG00000162461                                                                                                                                    
NBL1ENSG00000158747                                                                                                                                    
PLA2G2EENSG00000188784                                                                                                                                    
CYP2J2ENSG00000134716                                                                                                                                    
SLC25A44ENSG00000160785                                                                                                                                    
APOA2ENSG00000158874                                                                                                                                    
FMO1ENSG00000010932                                                                                                                                    
CYP26A1ENSG00000095596                                                                                                                                    
CYP2E1ENSG00000130649                                                                                                                                    
IGF2ENSG00000167244                                                                                                                                    
CYP2R1ENSG00000186104                                                                                                                                    
SLC25A45ENSG00000162241                                                                                                                                    
RNASE10ENSG00000182545                                                                                                                                    
TXNDC16ENSG00000087301                                                                                                                                    
VRK1ENSG00000100749                                                                                                                                    
CYP1A1ENSG00000140465                                                                                                                                    
HSD11B2ENSG00000176387                                                                                                                                    
DPEP3ENSG00000141096                                                                                                                                    
CTRB2ENSG00000168928                                                                                                                                    
CCL5ENSG00000271503                                                                                                                                    

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