Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CYP19A1ENSG00000137869                                                                                                                                    
CSNK1G1ENSG00000169118                                                                                                                                    
CYP1A2ENSG00000140505                                                                                                                                    
SDR42E2ENSG00000183921                                                                                                                                    
SDR42E1ENSG00000184860                                                                                                                                    
ERN1ENSG00000178607                                                                                                                                    
CYP4F22ENSG00000171954                                                                                                                                    
EIF2AK3ENSG00000172071                                                                                                                                    
UGT1A8ENSG00000242366                                                                                                                                    
UGT1A10ENSG00000242515                                                                                                                                    
UGT1A7ENSG00000244122                                                                                                                                    
UGT1A5ENSG00000240224                                                                                                                                    
UGT1A4ENSG00000244474                                                                                                                                    
UGT1A3ENSG00000243135                                                                                                                                    
UGT1A1ENSG00000241635                                                                                                                                    
CYP2D6ENSG00000100197                                                                                                                                    
UGT2B17ENSG00000197888                                                                                                                                    
UGT2B4ENSG00000156096                                                                                                                                    
SLC35D3ENSG00000182747                                                                                                                                    
SMOC2ENSG00000112562                                                                                                                                    

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