Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CPEENSG00000109472                                                                  1                                                                  
CASP3ENSG00000164305                                                                                                                                    
C6ENSG00000039537                                                                                                                                    
PIK3R1ENSG00000145675                                  1                        1                                                                1    1      
NPM1ENSG00000181163                                                      1                                                                              
RANBP9ENSG00000010017                                                                                                                                    
CSNK2BENSG00000204435                                                                                                                                    
TAB2ENSG00000055208                                                                                                                                    
PRKAR1BENSG00000188191                                                                                                                                    
RSPO2ENSG00000147655                                                                                                                                    
PLIN2ENSG00000147872                                                                                                                                    
HSPA5ENSG00000044574                                                                                                      1                              
TAB3ENSG00000157625                                                                                                                                    
SRPX2ENSG00000102359                                                                                                                                    
MMP23AENSG00000215914                                                                                                                                    
MBL2ENSG00000165471                                                                                                                                    
RARAENSG00000131759                                                                                                                                    
FGF22ENSG00000070388                                                                                                                                    
DEFB127ENSG00000088782                                                                                                                                    
DEFB118ENSG00000131068                                                                                                                                    

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