Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
KSR1ENSG00000141068                                                                                                                                    
SIRT2ENSG00000068903                                                                                                                                    
PPP5CENSG00000011485                                                                                                                                    
PLEKENSG00000115956                                                                                                                                    
GAD1ENSG00000128683                                                                                                                                    
RAPGEF4ENSG00000091428                                                                                                                                    
INHAENSG00000123999                                                                                                                                    
INPP5DENSG00000168918                                                                                                                                    
DEFB126ENSG00000125788                                                                                                                                    
TUBB1ENSG00000101162                                                                                                                                    
PPIL2ENSG00000100023                                                                                                                                    
BCRENSG00000186716                                                                  1                                                                  
HYAL3ENSG00000186792                                                                                                                                    
PARP14ENSG00000173193                                                                      1                                                              
TGFBIENSG00000120708                                                                                                                                    
TUBB2AENSG00000137267                                                                                                                                    
TUBB2BENSG00000137285                                                                                                                                    
APOMENSG00000204444                                                                                                                                    
OR6W1PENSG00000179420                                                                                                                                    
PDIA4ENSG00000155660                                                                                                                                    

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