Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
G6PDENSG00000160211                                                                                                                                    
PARK7ENSG00000116288                                                                                                                                    
PIK3CDENSG00000171608                                                                                                                                    
AHCYL1ENSG00000168710                                                                                                                                    
OR6K4PENSG00000180437                                                                                                                                    
TUBB8ENSG00000261456                                                                                                                                    
HPSE2ENSG00000172987                                                                                                                                    
FGF8ENSG00000107831                                                                                                                                    
THENSG00000180176                                                                                                                                    
CAPN5ENSG00000149260                                                                                                                                    
IRAK4ENSG00000198001                                                                                                                                    
MDM2ENSG00000135679                                                                                                                                    
NTN4ENSG00000074527                                                                                                                                    
PLA2G1BENSG00000170890                                                                                                                                    
OR4H12PENSG00000176312                                                                                                                                    
TGM1ENSG00000092295                                                                                                                                    
NFKBIAENSG00000100906      1                                                                                                                              
SCG5ENSG00000166922                                                                                                                                    
PDIA3ENSG00000167004                                                                                                                                    
PIK3R6ENSG00000276231                                                                                                                                    

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