Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
DEFB115ENSG00000215547                                                                                                                                    
GDF5ENSG00000125965                                                                                                                                    
SLC25A1ENSG00000100075                                                                                                                                    
AIFM3ENSG00000183773                                                                                                                                    
MAPK1ENSG00000100030              1                        1                                                                                              
JOSD1ENSG00000100221                                                                                                                                    
HDAC11ENSG00000163517                                                                                                                          1          
EXOGENSG00000157036                                                                                                                                    
TNIKENSG00000154310                                                                                                                                    
PAK2ENSG00000180370                                                                                                                                    
CXCL9ENSG00000138755                                                                                                                                    
CXCL10ENSG00000169245                                                                                                                                    
STK32AENSG00000169302                                                                                                                                    
F12ENSG00000131187                                                                                                                                    
C4BENSG00000224389                                                                                                                                    
SFRP1ENSG00000104332                                                                                                                                    
SLC25A32ENSG00000164933                                                                                                                                    
ERP44ENSG00000023318                                                                                                                                    
INPP5EENSG00000148384                                                                                                                                    
OCRLENSG00000122126                                                                                                                                    

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