Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PINK1ENSG00000158828                                                                                                                                    
EPHX1ENSG00000143819                                                                                                                                    
AKT3ENSG00000117020                                                                                                      1                              
SLC25A16ENSG00000122912                                                                                                                                    
AIFM2ENSG00000042286                                                                                                                                    
MTCH2ENSG00000109919                                                                                                                                    
ALDH3B1ENSG00000006534                                                                                                                                    
IGF1ENSG00000017427                                                                                                                                    
SLC25A15ENSG00000102743                                                                                                                                    
CALM1ENSG00000198668                                                                                                                                    
PCSK6ENSG00000140479                                                                                                                                    
PIK3R5ENSG00000141506                                                                                                                                    
TIMP2ENSG00000035862                                                                                                                                    
SLC25A10ENSG00000183048                                                                                                                                    
PRKD3ENSG00000115825                                                                                                                                    
ASTLENSG00000188886                                                                                                                                    
MGAT4AENSG00000071073                                                                                                                                    
TRIB3ENSG00000101255                                                                                                                                    
PRKCIENSG00000163558      1                                                                                                                              
PPP3CAENSG00000138814                                                                  1                                                                  

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