Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
LCATENSG00000213398                                                                                                                                    
DHODHENSG00000102967                                                                                                                                    
SLC22A31ENSG00000259803                                                                                                                                    
SPG7ENSG00000197912                                                                                                                                    
SPACA3ENSG00000141316                                                                                                                                    
AATKENSG00000181409                                                                                                                                    
SLC35G4ENSG00000236396                                                                                                                                    
AFG3L2ENSG00000141385                                                                                                                                    
KDSRENSG00000119537                                                                                                                                    
ATP9BENSG00000166377                                                                                                                                    
MBOAT7ENSG00000125505                                                                                                                                    
MBOAT2ENSG00000143797                                                                                                                                    
SLC35F6ENSG00000213699                                                                                                                                    
SLC30A6ENSG00000152683                                                                                                                                    
PIGFENSG00000151665                                                                                                                                    
VRK2ENSG00000028116                                                                                                                                    
MFSD9ENSG00000135953                                                                                                                                    
RHBDD1ENSG00000144468                                                                                                                                    
BCL2L1ENSG00000171552                                                                                                                                    
KCNK15ENSG00000124249                                                                                                                                    

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