Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PARP16ENSG00000138617                                                                                                                                    
SEC11AENSG00000140612                                                                                                                                    
HSD3B7ENSG00000099377                                                                                                                                    
ST3GAL2ENSG00000157350                                                                                                                                    
MBTPS1ENSG00000140943                                                                                                                                    
RHBDL3ENSG00000141314                                                                                                                                    
KCNH4ENSG00000089558                                                                                                                                    
SEC11CENSG00000166562                                                                                                                                    
LMAN1ENSG00000074695                                                                                                                          1          
BCL2ENSG00000171791                                                                                                                                    
CYP4F8ENSG00000186526                                                                                                                                    
CPT1CENSG00000169169                                                                                                                                    
HTRA2ENSG00000115317                                                                                                                                    
CHST10ENSG00000115526                                                                                                                                    
SMPD4ENSG00000136699                                                                                                                                    
UGT1A6ENSG00000167165                                                                                                                                    
ENTPD6ENSG00000197586                                                                                                                                    
ABHD12ENSG00000100997                                                                                                                                    
BPIENSG00000101425                                                                                                                                    
TMPRSS3ENSG00000160183                                                                                                                                    

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