Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TASP1ENSG00000089123                                                                                                                                    
GADL1ENSG00000144644                                                                                                                                    
USP4ENSG00000114316                                                                                                                                    
WDR1ENSG00000071127                                                                                                                          1          
METAP1ENSG00000164024                                                                                                                                    
TDO2ENSG00000151790                                                                                                                                    
AADATENSG00000109576                                                                                                                                    
ENC1ENSG00000171617                                                                                                                                    
RIOK2ENSG00000058729                                                                                                                                    
HMMRENSG00000072571                                                                                                                                    
NSD1ENSG00000165671                                      1                                1                                                    1          
SRPK1ENSG00000096063                                                                                                                                    
GLO1ENSG00000124767                                                                                                                                    
HSPB1ENSG00000106211                                                                                                                                    
NAMPTENSG00000105835                                                                                                                                    
AKR1B10ENSG00000198074                                                                                                                                    
AKR1B15ENSG00000227471                                                                                                                                    
ASH2LENSG00000129691                                                                                                                                    
JAK2ENSG00000096968                                                                  1                                                                  
PLAAENSG00000137055                                                                                                                                    

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