Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CASP4ENSG00000196954      1                                                                                                                              
USP2ENSG00000036672                                                                                                                                    
P3H3ENSG00000110811                                                                                                                                    
XRCC6BP1ENSG00000166896                                                                                                                                    
METAP2ENSG00000111142          1                                                                                                                          
HMGB1ENSG00000189403                                                                                                                                    
HIF1AENSG00000100644                                                                                                                                    
MFAP1ENSG00000140259                                                                                                                                    
PARP6ENSG00000137817                                                                                                                                    
TRIM16ENSG00000221926                                                                                                                                    
TRIM16LENSG00000108448                                                                                                                                    
PHOSPHO1ENSG00000173868                                                                                                                                    
PSMC5ENSG00000087191                                                                                                                                    
AXIN2ENSG00000168646                                                                                                                                    
RIOK3ENSG00000101782                                                                                                                                    
EEF2ENSG00000167658                                                                                                          1                          
FCGBPENSG00000275395                                                                                                                                    
ODC1ENSG00000115758                                                                                                                                    
PLCD4ENSG00000115556                                                                                                                                    
PLCB1ENSG00000182621                                                                                                                                    

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