Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CFDENSG00000197766                                                                                                                                    
MAP2K2ENSG00000126934                                                                                                      1                              
KLK10ENSG00000129451                                                                                                                                    
RASGRP3ENSG00000152689                                                                                                                                    
ATP6V1B1ENSG00000116039                                                                                                                                    
IGKV3-11ENSG00000241351                                                                                                                                    
IGKV4-1ENSG00000211598                                                                                                                                    
IGKV1-5ENSG00000243466                                                                                                                                    
IGKV3-15ENSG00000244437                                                                                                                                    
IGKV3-20ENSG00000239951                                                                                                                                    
IGKV2-30ENSG00000243238                                                                                                                                    
IGKV1-39ENSG00000242371                                                                                                                                    
IGKV1D-16ENSG00000241244                                                                                                                                    
FBLN7ENSG00000144152                                                                                                                                    
CASP10ENSG00000003400                                                                                                                          1          
PDYNENSG00000101327                                                                                                                                    
SNAP25ENSG00000132639                                                                                                                                    
PLCG1ENSG00000124181                                                              1    1                                                                  
LIPIENSG00000188992                                                                                                                                    
GGTLC3ENSG00000274252                                                                                                                                    

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